This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

推荐稀释比 WB:1/500-1/1000;FC:1/50-1/100;ELISA:1/10000

Western blot analysis of CD196 in K562 (1), THP-1 (2), and HL-60 (3) cell lysate using CD196 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。