Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200

Western blot analysis of IRAK4 in Jurkat, Hela lysates using IRAK4 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using IRAK4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry analysis of IRAK4 (green) in hela using IRAK4 antibody,and DAPI(blue)

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