This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

推荐稀释比 IHC: 1/100-1/200  ELISA: 1/10000

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded human liver cancer tissues using SIRT7 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。