CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

推荐稀释比 WB: 1/500-1/1000  IHC: 1/100-1/200  IF: 1/50-1/200  FC: 1/50-1/100   ELISA: 1/10000

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded human cervical cancer tissues using KAT2B antibody.

Immunocytochemistry

Immunocytochemistry analysis of KAT2B in  Hela cells using KAT2B antibody (green),and DAPI(blue). Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Flow

Flow Cytometry analysis of  MOLT4 cells using KAT2B antibody (green) and negative control (red).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。