The preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastroinTinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Pancreas using Somatostatin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.