This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
WB: 1/500-1/2000 IHC: 1/50-1/100
Western
Western blot analysis of DHPS in Human placenta lysates using DHPS antibody
Immunohistochemistry
Immunohistochemistry analysis of paraffin-embedded Human tonsil using DHPS antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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