DAP (death associated protein) kinase and ZIP kinase are members of a novel protein kinase family, the members of which have the capacity to mediate apoptosis through their catalytic activities. DAP kinase (DAPK) contains a “death domain” and has been shown to mediate IFN-γ-induced apoptosis. The introduction of DAPK into highly metastatic carcinoma clones lacking DAPK expression has been shown to result in the suppression of metastasis, thus linking suppression of apoptosis to metastasis.

Western

Western blot analysis of DAP Kinase 1 in HeLa lysates using DAP Kinase 1 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using DAP Kinase 1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence

Immunofluorescence analysis of DAP Kinase 1 in Hela using DAP Kinase 1 antibody.