脂肪酸2-羟基化通过YAP转录轴抑制结直肠癌肿瘤发生与转移
2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis
Sun Liang, Yang Xiaoqin, Huang Xiaoheng, Yao Yizhou, Wei Xiangyu, Yang Shugao, Zhou Diyuan, Zhang Wei, Long Zhimin, Xu Xiaoyan, Zhu Xinguo, He Songbing, Su Xiong
Journal:CANCER RESEARCH
IF:12.7
DOI:10.1158/0008-5472.CAN-20-1517
PMID:33203703
Published:2021-01-15
research field:
Abstract
These findings identify a novel metabolic mechanism regulating the tumor suppressor function of FA 2-hydroxylation in colorectal cancer.
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