Milrinone是一种通过抑制PDE3发挥强心和血管舒张作用的药物。
|
英文别名 (English Synonym) |
Milrinone |
|
中文名称 (Chinese Name) |
米力农 |
|
靶点 (Target) |
PDE |
|
通路 (Pathway) |
Protease/Metabolic Enzyme |
|
CAS号 (CAS NO.) |
78415-72-2 |
|
分子式 (Formula) |
C12H9N3O |
|
分子量 (Molecular Weight) |
211.22 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Santhosh KT, Elkhateeb O, Nolette N, Outbih O, Halayko AJ, Dakshinamurti S. Milrinone attenuates thromboxane receptor-mediated hyperresponsiveness in hypoxic pulmonary arterial myocytes. Br J Pharmacol. 2011 Jul,163(6):1223-36. doi: 10.1111/j.1476-5381.2011.01306.x. PMID: 21385177, PMCID: PMC3144536.[2]Hentschel T, Yin N, Riad A, Habbazettl H, Weimann J, Koster A, Tschope C, Kuppe H, Kuebler WM. Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failure. Anesthesiology. 2007 Jan,106(1):124-31. doi: 10.1097/00000542-200701000-00021. PMID: 17197854.
