Beclomethasone dipropionate是倍氯米松的前体药物，作为一种口服有效的糖皮质激素受体激动剂，通过激活该受体抑制炎症反应与细胞过度增殖，适用于哮喘的相关研究。
| 英文别名 (English Synonym) | Beclomethasone dipropionate |
| 中文名称 (Chinese Name) | 丙酸倍氯米松；二丙酸倍氯米松 |
| 靶点 (Target) | Glucocorticoid Receptor |
| 通路 (Pathway) | GPCR/G protein |
| CAS号 (CAS NO.) | 5534-09-8 |
| 分子式 (Formula) | C28H37ClO7 |
| 分子量 (Molecular Weight) | 521.04 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存，有效期3年
[1] Montalbano AM, Anzalone G, Albano GD, Sano CD, Gagliardo R, Bonanno A, Riccobono L, Nicolini G, Ingrassia E, Gjomarkaj M, Profita M. Beclomethasone dipropionate and formoterol reduce oxidative/nitrosative stress generated by cigarette smoke extracts and IL-17A in human bronchial epithelial cells. Eur J Pharmacol. 2013 Oct 15;718(1-3):418-27. doi: 10.1016/j.ejphar.2013.08.001. Epub 2013 Aug 19. PMID: 23969332.
[2] Hrvacić B, Bosnjak B, Tudja M, Mesić M, Merćep M. Applicability of an ultrasonic nebulization system for the airways delivery of beclomethasone dipropionate in a murine model of asthma. Pharm Res. 2006 Aug;23(8):1765-75. doi: 10.1007/s11095-006-9029-y. PMID: 16832613.
