磷酸吡哆醛是维生素B6的活性形式，它通过抑制逆转录酶的活性，在迟发性运动障碍症的研究中具有应用价值。
|
英文别名 (English Synonym) |
Pyridoxal phosphate |
|
中文名称 (Chinese Name) |
磷酸吡哆醛 |
|
靶点 (Target) |
Vitamin |
|
通路 (Pathway) |
Protease/Metabolic Enzyme |
|
CAS号 (CAS NO.) |
54-47-7 |
|
分子式 (Formula) |
C8H10NO6P |
|
分子量 (Molecular Weight) |
247.14 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Grin IR, Rieger RA, Zharkov DO. Inactivation of NEIL2 DNA glycosylase by pyridoxal phosphate reveals a loop important for substrate binding. Biochem Biophys Res Commun. 2010 Mar 26;394(1):100-5. doi: 10.1016/j.bbrc.2010.02.121. Epub 2010 Feb 20. PMID: 20175991; PMCID: PMC2857644.[2]Choi JM, Park HS, He MT, Kim YS, Kim HY, Lee AY, Cho EJ. Membrane-Free Stem Cells and Pyridoxal 5'-Phosphate Synergistically Enhance Cognitive Function in Alzheimer's Disease Mouse Model. Antioxidants (Basel). 2022 Mar 21;11(3):601. doi: 10.3390/antiox11030601. PMID: 35326251; PMCID: PMC8945526.
