骨吸收抑制剂|Pamidronate Disodium帕米膦酸二钠|CAS 57248-88-1（54618ES）

Pamidronate Disodium，又称帕米膦酸二钠，对磷酸钙具有很强的亲和性，能抑制骨吸收，强化骨骼，用于研究各种骨吸收类疾病的药物。

参考文献

[1] Ashton JA, Farese JP, Milner RJ, et al. Investigation of the effect of pamidronate disodium on the in vitro viability of osteosarcoma cellsfrom dogs. Am J Vet Res. 2005 May;66(5):885-91. doi: 10.2460/ajvr.2005.66.885(IF:1.07).

[2] Xu Y, Sun J, Yang X, et al. Pamidronate Disodium Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells In Vitro. J Oral Maxillofac Surg. 2017 Oct;75(10):2135-2143. doi: 10.1016/j.joms.2017.03.016(IF:1.781).

[3] Lv Y, Xia JY, Chen JY, et al. Effects of pamidronate disodium on the loss of osteoarthritic subchondral bone and the expression of cartilaginous and subchondral osteoprotegerin and RANKL in rabbits. BMC Musculoskelet Disord. 2014 Nov 6;15:370. doi: 10.1186/1471-2474-15-370(IF:2.002).

-25~-15℃保存，有效期3年。