Gliotoxin（胶霉毒素; 胶黏毒素; Aspergillin）是烟曲霉产生的真菌毒素，是一种免疫抑制剂，20S蛋白酶体抑制剂，可抑制巨噬细胞的吞噬作用及其他免疫细胞的免疫功能。Gliotoxin可抑制诱导型 NF-κB的活性进而诱导宿主细胞凋亡，还可以激活 PKA 并提高细胞内 cAMP的浓度。 

参考文献

[1] Vigushin DM, Mirsaidi N, Brooke G, et al. Gliotoxin is a dual inhibitor of farnesyltransferase and geranylgeranyltransferase I with antitumor activity against breast cancer in vivo. MEDICAL ONCOLOGY, 2004, 21(1):21-30.

[2] Jia XD, Chen FY, Pan WH, et al. Gliotoxin promotes Aspergillus fumigatus internalization into type II human pneumocyte A549 cells by inducing host phospholipase D activation. Microbes and infection / Institut Pasteur, 2014, 16(6):491-501.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。