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重组人TIM-3/HAVCR2蛋白(Llama Fc标签) Human TIM-3/HAVCR2 Protein(96842ES)

Recombinant Human TIM-3/HAVCR2 Protein,Llama Fc Tag
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产品应用
产品介绍
Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene.TIM3 is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8 T-cell exhaustion. TIM3 has also been shown as a CD4 Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.
产品性质
产品特色
高活性、高纯度、低内毒素、高稳定性
应用案例
ELISA Data: Immobilized Human TIM-3, LIama Fc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-TIM-3 Antibody, hFc Tag with the EC50 of 0.14μg/ml determined by ELISA.
存储条件
-25~-15℃保存,收到货之日起,有效期1年。复溶后, -85~-65℃保存,3个月有效期。避免反复冻融。
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