CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.

推荐稀释比 WB:1/1000-1/2000; IHC:1/100-1/200; IF:1/50-1/200; FC:1/50-1/100

Western blot analysis of CD81 in RAW 264.7 lysates using CD81 antibody.

Western blot analysis of CD81 in Ramos lysates using CD81 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using CD81 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.