HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200;IP:1/20

Western blot analysis of HMGA1 in Hela, C6, MCF-7 lysates using HMGA1 antibody.

Immunocytochemistry analysis of HMGA1(green) in Hela using HMGA1 antibody,and DAPI(blue)

Immunohistochemistry analysis of paraffin-embedded Human tonsil using HMGA1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。