GLI belongs to the Kruppel family of zinc finger proteins that includes three mammalian GLI proteins: GLI1, GLI2, and GLI3. Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of GLI1 in Raji and HepG2 lysates using GLI1 antibody

Immunohistochemistry analysis of paraffin-embedded Human liver cancer using GLI1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.