重组小鼠FcγRIV/CD16-2蛋白(His标签) Mouse Fc gamma RIV/CD16-2 Protein（95917ES）

Fc γ RIV (Low affinity immunoglobulin gamma Fc region receptor IV), also known as CD16-2 (Fc γ RIV), belongs to the Fc γ receptor family. Fc γ receptors can be divided into three types: Fc γ RI (CD64), Fc γ RII (CD32) and Fc γ RIII (CD16). Fc γ RI (CD64) has a high affinity for IgG monomers, while Fc γ RII (CD32) and Fc γ RIII (CD16) have relatively low affinity for IgG. Human CD16 is encoded by two genes, Fc γ RIIIA and Fc γ RIIIB. The gene sequence of CD16-2 is more similar to human Fc γ RIIIA protein. Fc γ RIV binding with IgG2a can promote osteocyte differentiation, while binding with IgE can promote macrophage-mediated phagocytosis, antigen presentation and pro-inflammatory cytokines production.

高纯度、高活性、低内毒素、高批间一致性

                       SDS-PAGE

           The purity is greater than 95%.

                          SPR

             Anti-His antibody Immobilized on CM5 Chip captured CD16-2 His Tag, Mouse can bind Pertuzumab with an affinity constant of 0.211 μM as determined in SPR assay .

-25 ~ -15℃保存，收到货之后有效期1年。
复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。