Isoxsuprine (hydrochloride)为β肾上腺素受体激动剂，兼具血管扩张活性与NMDA受体拮抗作用。
| 英文别名 (English Synonym) | Isoxsuprine (hydrochloride) |
| 中文名称 (Chinese Name) | 异舒普林盐酸盐；盐酸异克舒令 |
| 靶点 (Target) | Adrenergic Receptor |
| 通路 (Pathway) | GPCR/G protein |
| CAS号 (CAS NO.) | 579-56-6 |
| 分子式 (Formula) | C18H23NO3·HCl |
| 分子量 (Molecular Weight) | 337.8 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存，有效期3年
[1] Kretschy N, Teichmann M, Kopf S, Atanasov AG, Saiko P, Vonach C, Viola K, Giessrigl B, Huttary N, Raab I, Krieger S, Jäger W, Szekeres T, Nijman SM, Mikulits W, Dirsch VM, Dolznig H, Grusch M, Krupitza G. In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen. Br J Cancer. 2013 Feb 19;108(3):570-8. doi: 10.1038/bjc.2012.580. Epub 2013 Jan 8. PMID: 23299527; PMCID: PMC3593542.[2]Hill JW, Thompson JF, Carter MB, Edwards BS, Sklar LA, Rosenberg GA. Identification of isoxsuprine hydrochloride as a neuroprotectant in ischemic stroke through cell-based high-throughput screening. PLoS One. 2014 May 7;9(5):e96761. doi: 10.1371/journal.pone.0096761. PMID: 24804769; PMCID: PMC4013073.
