Curcumol，又称莪术醇、姜黄醇、莪黄醇或姜黄环氧醇，是常见的传统中药，来源于姜黄和玫瑰，具有抗肿瘤、抗炎和抗病毒活性。在多种癌细胞中，Curcumol通过调节关键信号通路（如NF-κB、MAPK/ERK或PI3K/Akt）活性诱导细胞凋亡。

参考文献

[1].Zhang W, et al. Curcumol induces apoptosis via caspases-independent mitochondrial pathway in human lung adenocarcinoma ASTC-a-1 cells. Med Oncol, 2011;28(1), 307-314.

[2].Wang J, et al. Curcumol induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3β/cyclin D1 pathway. J Ethnopharmacol. 2018;210:1-9.

[3].Ning L, et al. Curcumol Suppresses Breast Cancer Cell Metastasis by Inhibiting MMP-9 Via JNK1/2 and Akt-Dependent NF-κB Signaling Pathways. Integr Cancer Ther. 2016;15(2):216-225.

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