Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

推荐稀释比 WB:1/500-1/1000; IF:1/100-1/200; FC:1/50-1/100; IP:1/20-1/50

Western blot analysis of PI3 Kinase p85 alpha in Jurkat, Rat Brain, C6, CHO-K1 lysates using PI3 Kinase p85 alpha antibody.

Immunocytochemistry analysis of PI3 Kinase p85 alpha (green) in MCF-7 using PI3 Kinase p85 alpha antibody,and DAPI(blue)

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。