Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.

推荐稀释比 WB:1/500-1/1000; FC:1/50-1/100

Western blot analysis of Toll-Like Receptor 4 in HL-60 lysates using Toll-Like Receptor 4 antibody.

Flow cytometry analysis of Toll-Like Receptor 4 in U251 (right histogram) stained with Toll-Like Receptor 4 antibody compared to a negative control cell (left histogram).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。