This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

推荐稀释比 WB:1/1000-1/2000; IP:1/50; IF:1/50-1/200

Western blot analysis of xCT in Rat cerebellum lysates using xCT antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。