Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.

推荐稀释比 WB:1/500-1/2000; IHC:1/50-1/300; IF:1/50-1/200

Western blot analysis of Cleaved-Caspase3 in various lysates using Cleaved-Caspase3 p17 antibody.

Immunohistochemistry analysis of paraffin-embedded mouse colon tissue using Cleaved-Caspase3 p17 antibody High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.