Phospho-LIMK1/2 (Thr508/505) Rabbit pAb
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Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159, PubMed:11832213, PubMed:12807904, PubMed:15660133, PubMed:16230460, PubMed:18028908, PubMed:22328514, PubMed:23633677). Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue located in its activation loop (PubMed:10436159).
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推荐稀释比 WB:1/500-1/3000;IHC:1/50-1/100
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-25 ~ -15℃保存,收到货之后有效期1年,避免反复冻融。

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