Ras (G12D) is one type of Ras missense mutations at the codon 12. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G12D mutation results in decreased GTPase activity and constitutive signaling. This mutation is found in many types of human cancers.

推荐稀释比 WB:1/100-1/1000;ICC/IF:1/50-1/100;IHC-P:1/50-1/100;ELISA:1/100-1/3000

Western blot analysis of recombinant Ras WT and G12D proteins. Equal amounts of purified Ras WT (lane 1) and G12D (lane 2) proteins were loaded and blotted with anti-Ras G12D mouse monoclonal antibody (Top panel). Input control (bottom panel) was blotted with rabbit polyclonal anti-Ras antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。