Butyrylation of lysine, structurally similar to lysine acetylation and lysine propionylation, is a newly identified reversible modification controlling protein activity. With integrated proteomic approaches and biochemistry analysis, lysine butyrylation are widely distributed in wide ranges of prokaryotic and eukaryotic histones and non-histone substrates. Lysine butyrylation may play a vital role in the regulation of transcriptional regulation, tumorigenesis, chromatin dynamics, and plasticity.

推荐稀释比 WB:1/500-1/1000