The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.

推荐稀释比 WB:1/500-1/1000;FC:1/50-1/100;ELISA:1/10000

Flow Cytometry analysis of SK-N-SH cells using CHRND antibody (green) and negative control (red).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。