PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200;IP:1/50

Western blot analysis of Phospho-PP2A alpha (Y307) in (1) rat kidney lysates; (2) A431 lysates treated with EGF using Phospho-PP2A alpha (Tyr307) antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。