Clusterin (CLU, apolipoprotein J) is a multifunctional glycoprotein that is expressed ubiquitously in most tissues. Clusterin functions as a secreted chaperone protein that interacts with and stabilizes stress-induced proteins to prevent their precipitation. Research studies show that clusterin plays a protective role in Alzheimer’s disease by sequestering amyloid β(1-40) peptides to form long-lived, stable complexes, which prevents amyloid fibril formation.

推荐稀释比 IHC:1/100-1/200

Immunohistochemistry analysis of paraffin-embedded Tonsill using Clusterin antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

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