This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq, Jul 2008]

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Immunohistochemistry analysis of paraffin-embedded Carcinoma of Human kidney tissue using EXOSC1 antibody.High-pressure and temperature Tris-EDTA pH 8.5 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -106°C long term. Avoid freeze/thaw cycles.