Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.

推荐稀释比 WB:1/500-1/1000;FC:1/50-1/100

Western blot analysis of Rad21 in HeLa lysates using Rad21 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。