CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

推荐稀释比 IHC:1/100-1/200;FC:1/50-1/100;ELISA:1/10000

Immunohistochemistry analysis of paraffin-embedded human cervical cancer tissues using DNMT3A antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。