Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of B Raf in MDA-MB-468, T47D, MCF-7, HCT116, C2C12, 3T3 and Hela lysates using B Raf antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。