MKK7 is strongly activated by TNF-α, as well as other environmental stresses, whereas SEK1/MKK4, which activates both p38 and SAPK/JNK pathways, is not activated by TNF-α. Sequence alignment of the activation loop of the MAP kinase kinase family members indicates that Ser271 and Thr275 are potential phosphorylation sites that are crucial for the kinase acivity.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;FC:1/50-1/100

Western blot analysis of MEK7 in HeLa lysates using MEK7 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。