Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of p60 katanin in K562, Hela lysates using p60 Katanin antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。