Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase . Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of ENSA in rat Brain, C6, 3T3, Hela lysates using ENSA antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。