Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of PU.1/Spi1 in Daudi, mouse liver lysates using SPI1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。