PHLDA2 Rabbit pAb
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TSSC3 (Tumor-suppressing STF cDNA 3 protein), also known as PHLDA2 (pleckstrin homology-like domain family A member 2), BWR1C, HLDA2 or IPL, is a cytoplasmic protein that is involved in fetal and placental growth. Expressed at high levels in placenta and adult prostate and at low levels in liver, lung and brain, TSSC3 is an apoptosis-related protein that acts as a negative growth regulator and is expressed during normal human development. TSSC3, a protein expressed from the maternal allele, is imprinted on placenta, liver and fetal tissues during embryogenesis and is removed once development is complete. Defects or alterations in the gene encoding TSSC3 are associated with several afflictions such as lung, ovarian and breast cancer, rhabdomyosarcoma, Beckwith-Wiedemann syndrome, Wilms tumor, low birth weight and adrenocortical carcinoma. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity).

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推荐稀释比 WB:1/500-1/1000;IF:1:50/1:200
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-25 ~ -15℃保存,收到货之后有效期1年,避免反复冻融。

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