Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.

推荐稀释比 WB:1/500-1/1000;IF:1:50/1:200

Western blot analysis of RSK1 p90 in Hela and 3T3 lysates using p90RSK (Ab348) antibody.

Immunofluorescence analysis of RSK1 p90 in Hela using p90RSK (Ab348) antibody.

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