This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

推荐稀释比 IF:1/50-1/200;ELISA:1/10000

Immunofluorescence analysis of Melatonin Receptor 1A in HepG2 cells using Melatonin Receptor 1A antibody. Sample with blocking peptide on the right.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。