The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.

稀释比 WB:1/500-1/1000

Western blot

Western blot analysis of TBK1 in HeLa(WT) and TBK1-Knockdown HeLa(KD) using TBK1 antibody.

Western blot analysis of TNK1/NAK in Jurkat, C6, CHO-K1, Hela lysates using TNK1/NAK antibody.

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