Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. GAPDH is constitutively abundant expressed in almost cell types at high levels, therefore antibodies against GAPDH are useful as loading controls for Western Blotting. Some pathology factors, such as hypoxia and diabetes, increased or decreased GAPDH expression in certain cell types.

推荐稀释倍数，WB: 1/1000—1/5000

冰袋（wet ice）运输。-20℃保存，避免反复冻融。

[1] Chen H, Guo Q, Chu Y, et al. Smart hypoxia-responsive transformable and charge-reversible nanoparticles for the deep penetration and tumor microenvironment modulation of pancreatic cancer [published online ahead of print, 2022 May 25]. Biomaterials. 2022;287:121599. doi:10.1016/j.biomaterials.2022.121599(IF:12.479)

[2] Gong X, Pu X, Wang J, et al. Enhancing of Nanocatalyst-Driven Chemodynaminc Therapy for Endometrial Cancer Cells Through Inhibition of PINK1/Parkin-Mediated Mitophagy. Int J Nanomedicine. 2021;16:6661-6679. Published 2021 Sep 29. doi:10.2147/IJN.S329341(IF:6.400)

[3] Bu S, Wang Q, Sun J, Li X, Gu T, Lai D. Melatonin suppresses chronic restraint stress-mediated metastasis of epithelial ovarian cancer via NE/AKT/β-catenin/SLUG axis [published correction appears in Cell Death Dis. 2020 Sep 8;11(9):726]. Cell Death Dis. 2020;11(8):644. Published 2020 Aug 18. doi:10.1038/s41419-020-02906-y(IF:6.304)

[4] Wang Y, Chen J, Gao WQ, Yang R. METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism. Cell Death Discov. 2022;8(1):143. Published 2022 Mar 30. doi:10.1038/s41420-022-00939-0(IF:5.241)

[5] Bu S, Li B, Wang Q, et al. Epithelial ovarian cancer stem‑like cells are resistant to the cellular lysis of cytokine‑induced killer cells via HIF1A‑mediated downregulation of ICAM‑1. Int J Oncol. 2019;55(1):179-190. doi:10.3892/ijo.2019.4794(IF:3.571)