Abstract

The aim of this study is to prepare hybrid polymer–ceramic dental materials for chairside computer-aided design/computer-aided manufacturing (CAD/CAM) applications. The hybrid polymer–ceramic materials were fabricated via infiltrating polymerizable monomer mixtures into sintered hydroxyapatite/bioactive glass (HA/BAG) ceramic blocks and thermo-curing. The microstructure was observed by scanning electron microscopy and an energy-dispersive spectrometer. The phase structure was analyzed by X-ray diffraction. The composition ratio was analyzed by a thermogravimetric analyzer. The hardness was measured by a Vickers hardness tester. The flexural strength, flexural modulus, and compressive strength were measured and calculated by a universal testing machine. The growth of human gingival fibroblasts was evaluated by a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) colorimetric assay and immunofluorescence staining. The results showed that the sintering temperature and BAG content affected the mechanical properties of the hybrid polymer–ceramic materials. The X-ray diffraction analysis showed that high-temperature sintering promoted the partial conversion of HA to β-tricalcium phosphate. The values of the hardness, flexural strength, flexural modulus, and compressive strength of all the hybrid polymer–ceramic materials were 0.89–3.51 GPa, 57.61–118.05 MPa, 20.26–39.77 GPa, and 60.36–390.46 MPa, respectively. The mechanical properties of the hybrid polymer–ceramic materials were similar to natural teeth. As a trade-off between flexural strength and hardness, hybrid polymer–ceramic material with 20 wt.% BAG sintered at 1000 °C was the best material. In vitro experiments confirmed the biocompatibility of the hybrid polymer–ceramic material. Therefore, the hybrid polymer–ceramic material is expected to become a new type of dental restoration material.Keywords:hybrid polymer–ceramic;hydroxyapatite;bioactive glass;mechanical properties;human gingival fibrobl