PLLA-Mg₆₅Zn₃₀Ca₅复合材料作为骨植入可降解生物材料的研究

Abstract

PLLA-magnesium composites have been widely investigated as potential biodegradable materials for bone implants. Lower/higher corrosion resistance of the crystalized/amorphous magnesium alloys allows tailoring of biodegradability rate. In this work, the amorphous Mg 65 Zn 30 Ca 5 was investigated versus traditional crystalized Mg 65 Zn 30 Ca 5 , and a PLLA-Mg 65 Zn 30 Ca 5 composite has been successfully fabricated using hot injection process. Furthermore, the high corrosion resistance of the amorphous Mg 65 Zn 30 Ca 5 prevented the high alkalization and deterioration of mechanical strength. In addition, the high Zn content intended to improve the glass forming ability, also enhances the anti-bacterial property of the PLLA-Mg 65 Zn 30 Ca 5 composite. The remarkable performance of the PLLA-Mg 65 Zn 30 Ca 5 composite shows its promising application in bone repair and tissue regeneration.