IPO7 promotes pancreatic cancer progression via regulating ERBB pathway
Li Ming, Xu Dongqiang, Zhan Yijun, Tan Shiyun
Journal：Clinics
IF：2.9
DOI：10.1016/j.clinsp.2022.100044
PMID：35588577
Published：2022-06-06
research field：分子生物学内分泌学代谢遗传学肝病学
Abstract
Highlights IPO7 remarkably enhanced pancreatic cancer cell proliferation, migration and invasion and suppressed apoptosis. IPO7 facilitated the malignant phenotype of pancreatic cancer cells by up-regulating ERBB2. Knockdown of IPO7 inhibited tumor growth and lung metastasis in vivo.
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