GSK3通过抑制β-catenin/Akt激活调控Foxo1-Klf2-S1P1轴驱动胸腺细胞迁出
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt
Chenfeng Liu, Lei Ma, Yuxuan Wang, Jiayi Zhao, Pengda Chen, Xian Chen, Yingxin Wang, Yanyan Hu, Yun Liu, Xian Jia, Zhanghua Yang, Xingzhi Yin, Jianfeng Wu, Suqin Wu, Haiping Zheng, Xiaohong Ma, Xiufe
Journal：Science Advances
IF：14.14
DOI：10.1126/sciadv.abg6262
PMID：
Published：2021-10-08
research field：分子生物学细胞生物学免疫学
Abstract
GSK3 controls thymocyte egress by regulating a Foxo1-Klf2-S1P1 axis through dampening β-catenin–mediated Akt activation.
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