Receptor activator of nuclear factor κB (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone.

高纯度、高活性、低内毒素、高批间一致性

              SDS-PAGE

    Human RANKL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

                  SEC-HPLC

                ELISA Data

Immobilized Human RANKL, No Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human TNFRSF11A, hFc Tag with the EC50 of 13.6 ng/ml determined by ELISA

                         SPR  Data

Human TNFRSF11B, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human RANKL, No Tag with an affinity constant of 0.030 nM as determined in SPR assay

-25 ~ -15℃保存，收到货之后有效期1年。复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。