2-Deoxy-D-glucose是一种葡萄糖类似物和葡萄糖代谢抑制剂,它通过靶向己糖激酶来抑制糖酵解过程。
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英文别名 (English Synonym) |
2-Deoxy-D-glucose |
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中文名称 (Chinese Name) |
2-脱氧-D-葡萄糖 |
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靶点 (Target) |
Hexokinase |
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通路 (Pathway) |
Others |
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CAS号 (CAS NO.) |
154-17-6 |
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分子式 (Formula) |
C6H12O5 |
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分子量 (Molecular Weight) |
164.16 |
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纯度 (Purity) |
≥98% |
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溶解性 (Solubility) |
溶于水 |
-25~-15℃保存，有效期3年。
[1] Zhu Z, Jiang W, McGinley JN, Thompson HJ. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1,65(15):7023-30. doi: 10.1158/0008-5472.CAN-05-0453. PMID: 16061689.[2]Ueyama A, Sato T, Yoshida H, Magata K, Koga N. Nonradioisotope assay of glucose uptake activity in rat skeletal muscle using enzymatic measurement of 2-deoxyglucose 6-phosphate in vitro and in vivo. Biol Signals Recept. 2000 Sep-Oct,9(5):267-74. doi: 10.1159/000014649. PMID: 10965062.
