Thymol是从唇形科等多种植物精油中分离的主要单萜酚,作为TRPA1激动剂,它具有诱导癌细胞凋亡以及抗氧化、抗炎、抗菌和抗真菌的多重生物活性。
|
英文别名 (English Synonym) |
Thymol |
|
中文名称 (Chinese Name) |
百里酚 |
|
靶点 (Target) |
|
|
通路 (Pathway) |
Immunology/Inflammation |
|
CAS号 (CAS NO.) |
89-83-8 |
|
分子式 (Formula) |
C10H14O |
|
分子量 (Molecular Weight) |
150.22 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Li T, Shi J, Wang L, Qin X, Zhou R, Dong M, Ren F, Li X, Zhang Z, Chen Y, Liu Y, Piao Y, Shi Y, Xu S, Chen J, Li J. Thymol targeting interleukin 4 induced 1 expression reshapes the immune microenvironment to sensitize the immunotherapy in lung adenocarcinoma. MedComm (2020). 2023 Aug 30,4(5):e355. doi: 10.1002/mco2.355. PMID: 37655051, PMCID: PMC10466095.[2]De La Chapa JJ, Singha PK, Lee DR, Gonzales CB. Thymol inhibits oral squamous cell carcinoma growth via mitochondria-mediated apoptosis. J Oral Pathol Med. 2018 Aug,47(7):674-682. doi: 10.1111/jop.12735. Epub 2018 Jun 9. PMID: 29777637, PMCID: PMC6105452.
